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if you take in less energy then you take
out then you will lose weight and and
that idea of course it has some truth to
it but then it also oversimplifies the
situation and we know that this is also
definitely not the full answer to it so
my name is Aaron Segal I'm a researcher
at the Weizmann Institute of Science you
can have a diet where people even eat
more calories than some other person yet
they still lose more weight and even the
same person on diet a can eat say 2,000
calories and gain weight but then on
another diet that person would eat 2500
calories but they would be losing weight
and and the reason is because the foods
in these different diets may be very
different and may be processed very
differently by the individual and it has
to do with the amount of energy that
that individual may be able to extract
from one diet compared to the other and
we really think that a key aspect for
measuring that has to do with your blood
glucose level response to those foods
because that really dictates then the
amount of insulin that your body
secretes and that is directly affecting
the amount of fat storage that will be
caused by consumption of these foods one
of the reasons why you really see this
phenomena that on the same food some
person would gain weight and another
person would lose weight a lot of that
we believe has to do with differences
that we have in our gut bacteria because
the gut bacteria would be processing and
being involved in metabolizing the foods
very differently in each person so each
of us actually has a tremendous amount
of different bacteria living within
within our body some bacteria will
thrive on some food and other bacteria
will thrive on other foods they're
really heavily intertwined with our
metabolism and have an enormous impact
on our processing of food and on our
health and disease and they've been
linked to many different disease to
obesity
diabetes heart disease and even to
cancer and neurological disease we are
still as a scientific community trying
to understand what is a good and what is
a bad bacterial composition and how we
can also change that with diet and this
is very much an active field of research
that we are trying to understand but in
the meantime we've been able to profile
individuals gut bacterial composition
and based on their composition identify
foods that would be fitting and matching
their own bacterial composition so while
we still do not understand the full way
by which we can affect the gut bacteria
for the better
we can utilize and harness the
information in the gut bacterial
composition in order to tailor the diet
of an individual to find foods that
would be optimal for that person
you